[Debian-med-packaging] Bug#739508: ITP: fitgpc -- fitting genome coverage distributions with mixture models

Andreas Tille tille at debian.org
Wed Feb 19 14:56:41 UTC 2014


Package: wnpp
Severity: wishlist
Owner: Andreas Tille <tille at debian.org>

* Package name    : fitgpc
  Version         : 0.0.20130418
  Upstream Author : Martin S. Lindner <LindnerM at rki.de>
* URL             : http://sourceforge.net/projects/fitgcp/files/
* License         : BSD
  Programming Lang: Python
  Description     : fitting genome coverage distributions with mixture models
 Genome coverage, the number of sequencing reads mapped to a position in
 a genome, is an insightful indicator of irregularities within sequencing
 experiments. While the average genome coverage is frequently used within
 algorithms in computational genomics, the complete information available
 in coverage profiles (i.e. histograms over all coverages) is currently
 not exploited to its full extent. Thus, biases such as fragmented or
 erroneous reference genomes often remain unaccounted for. Making this
 information accessible can improve the quality of sequencing experiments
 and quantitative analyses.
 .
 fitGCP is a framework for fitting mixtures of probability distributions
 to genome coverage profiles. Besides commonly used distributions, fitGCP
 uses distributions tailored to account for common artifacts. The mixture
 models are iteratively fitted based on the Expectation-Maximization
 algorithm.


This package is maintained by the Debian Med team and the packaging
is available at

   git://anonscm.debian.org/debian-med/fitgpc.git



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