[Debian-med-packaging] Bug#776655: ITP: rna-star -- ultrafast universal RNA-seq aligner

Andreas Tille tille at debian.org
Fri Jan 30 16:13:32 UTC 2015


Package: wnpp
Severity: wishlist
Owner: Andreas Tille <tille at debian.org>

* Package name    : rna-star
  Version         : 2.4.0i
  Upstream Author : Alexander Dobin <dobin at cshl.edu>
* URL             : https://github.com/alexdobin/STAR
* License         : MIT
  Programming Lang: C++
  Description     : ultrafast universal RNA-seq aligner
 Spliced Transcripts Alignment to a Reference (STAR) software based on a
 previously undescribed RNA-seq alignment algorithm that uses sequential
 maximum mappable seed search in uncompressed suffix arrays followed by
 seed clustering and stitching procedure. STAR outperforms other aligners
 by a factor of >50 in mapping speed, aligning to the human genome 550
 million 2 × 76 bp paired-end reads per hour on a modest 12-core server,
 while at the same time improving alignment sensitivity and precision. In
 addition to unbiased de novo detection of canonical junctions, STAR can
 discover non-canonical splices and chimeric (fusion) transcripts, and is
 also capable of mapping full-length RNA sequences. Using Roche 454
 sequencing of reverse transcription polymerase chain reaction amplicons,
 the authors experimentally validated 1960 novel intergenic splice
 junctions with an 80-90% success rate, corroborating the high precision
 of the STAR mapping strategy.

This package is maintained by the Debian Med team at
Vcs-Svn: svn://anonscm.debian.org/debian-med/trunk/packages/rna-star/trunk/



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